Experiment Overview
| Repository ID: | FR-FCM-Z4MQ | Experiment name: | CyTOF profiling of whole blood samples from infliximab treated Crohn's disease patients | MIFlowCyt score: | 68.00% |
| Primary researcher: | Shiran Vainberg | PI/manager: | Shai Shen-Orr | Uploaded by: | Shiran Vainberg |
| Experiment dates: | 2021-11-02 - 2024-11-03 | Dataset uploaded: | Nov 2021 | Last updated: | Dec 2023 |
| Keywords: | [CyTOF] [IBD] [Crohn's disease] [Anti-TNF antibodies] [Infliximab] | Manuscripts: | |||
| Organizations: |
Technion, Immunology, Rappaport Institute of Medical Research, Faculty of Medicine, Haifa, (Israel)
Technion, Immunology, Rappaport Institute of Medical Research, Faculty of Medicine, Haifa, (Israel) |
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| Purpose: | CyTOF profiling of whole blood samples from infliximab treated Crohn's disease patients at three time points: pre-treatment, two weeks and fourteen weeks post first treatment | ||||
| Conclusion: | Personalized treatment of complex diseases is an unmet medical need pushing towards drug biomarker identification of one drug-disease combination at a time. Here, we used a novel computational approach for modeling cell-centered individual-level network dynamics from high-dimensional blood data to predict infliximab response and uncover individual variation of non-response. We identified and validated that the RAC1-PAK1 axis is predictive of infliximab response in inflammatory bowel disease. Intermediate monocytes, which closely correlated with inflammation state, play a key role in the RAC1-PAK1 responses, supporting their modulation as a therapeutic target. This axis also predicts response in Rheumatoid arthritis, validated in three public cohorts. Our findings support pan-disease drug response diagnostics from blood, implicating common mechanisms of drug response or failure across diseases. | ||||
| Comments: | None | ||||
| Funding: | This work was supported by funding of the Helmsley Charitable Trust. | ||||
| Quality control: | A panel of 37 antibodies were used for CyTOF analysis. The antibodies were validated for specificity to their target by their manufacturers. Optimal staining concentration for each antibody was determined in titration experiments. Inflamed and healthy control samples were used to evaluate staining. Batch effects were tested between runs. Cryopreservation effect was evaluated by comparison to fresh samples, to optimize sample storage. | ||||
Experiment variables
| Conditions | |
|---|---|
| · Responder | HR-20-V1_cells_found_normalized_Granulocytes.fcs · HR-20-V1_cells_found_normalized_Lymphocytes.fcs · HR-20-V2_cells_found_normalized_Granulocytes.fcs · HR-20-V2_cells_found_normalized_Lymphocytes.fcs · HR-20-V3_cells_found_normalized_Granulocytes.fcs · HR-20-V3_cells_found_normalized_Lymphocytes.fcs · HR-22-V1_cells_found_normalized_Granulocytes.fcs · HR-22-V1_cells_found_normalized_Lymphocytes.fcs · HR-22-V2_cells_found_normalized_Granulocytes.fcs · HR-22-V2_cells_found_normalized_Lymphocytes.fcs · HR-22-V3_cells_found_normalized_Granulocytes.fcs · HR-22-V3_cells_found_normalized_Lymphocytes.fcs · HR-24-V1_cells_found_normalized_Granulocytes.fcs · HR-24-V1_cells_found_normalized_Lymphocytes.fcs · HR-24-V2_cells_found_normalized_Granulocytes.fcs · HR-24-V2_cells_found_normalized_Lymphocytes.fcs · HR-24-V3_cells_found_normalized_Granulocytes.fcs · HR-24-V3_cells_found_normalized_Lymphocytes.fcs · HR-28-V1_cells_found_normalized_Granulocytes.fcs · HR-28-V1_cells_found_normalized_Lymphocytes.fcs · HR-28-V2_cells_found_normalized_Granulocytes.fcs · HR-28-V2_cells_found_normalized_Lymphocytes.fcs · HR-28-V3_cells_found_normalized_Granulocytes.fcs · HR-28-V3_cells_found_normalized_Lymphocytes.fcs · HR-29-V1_cells_found_normalized_Granulocytes.fcs · HR-29-V1_cells_found_normalized_Lymphocytes.fcs · HR-29-V2_cells_found_normalized_Granulocytes.fcs · HR-29-V2_cells_found_normalized_Lymphocytes.fcs · HR-29-V3_cells_found_normalized_Granulocytes.fcs · HR-29-V3_cells_found_normalized_Lymphocytes.fcs · HR-30-V1_cells_found_normalized_Granulocytes.fcs · HR-31-V1_1_cells_found_normalized_Granulocytes.fcs · HR-31-V1_1_cells_found_normalized_Lymphocytes.fcs · HR-31-V2_1_cells_found_normalized_Granulocytes.fcs · HR-31-V2_1_cells_found_normalized_Lymphocytes.fcs · HR-31-V3_cells_found_normalized_Granulocytes.fcs · HR-31-V3_cells_found_normalized_Lymphocytes.fcs · HR-33-V1_cells_found_normalized_Lymphocytes.fcs · HR-33-V2_cells_found_normalized_Granulocytes.fcs · HR-33-V2_cells_found_normalized_Lymphocytes.fcs · HR-33-V3_cells_found_normalized_Granulocytes.fcs · HR-33-V3_cells_found_normalized_Lymphocytes.fcs · HR-35-V1_cells_found_normalized_Granulocytes.fcs · HR-35-V1_cells_found_normalized_Lymphocytes.fcs · HR-35-V2_cells_found_normalized_Granulocytes.fcs · HR-35-V2_cells_found_normalized_Lymphocytes.fcs · HR-35-V3_cells_found_normalized_Granulocytes.fcs · HR-35-V3_cells_found_normalized_Lymphocytes.fcs · HR-39-V1_cells_found_normalized_Granulocytes.fcs · HR-39-V1_cells_found_normalized_Lymphocytes.fcs · HR-39-V2_cells_found_normalized_Granulocytes.fcs · HR-39-V2_cells_found_normalized_Lymphocytes.fcs · HR-39-V3_cells_found_normalized_Granulocytes.fcs · HR-39-V3_cells_found_normalized_Lymphocytes.fcs · HR-40-V1_cells_found_normalized_Granulocytes.fcs · HR-40-V1_cells_found_normalized_Lymphocytes.fcs · HR-40-V2_cells_found_normalized_Granulocytes.fcs · HR-40-V2_cells_found_normalized_Lymphocytes.fcs · HR-40-V3_cells_found_normalized_Granulocytes.fcs · HR-40-V3_cells_found_normalized_Lymphocytes.fcs · HR-42-V1_cells_found_normalized_Granulocytes.fcs · HR-42-V1_cells_found_normalized_Lymphocytes.fcs · HR-42-V2_cells_found_normalized_Granulocytes.fcs · HR-42-V2_cells_found_normalized_Lymphocytes.fcs · HR-42-V3_cells_found_normalized_Granulocytes.fcs · HR-42-V3_cells_found_normalized_Lymphocytes.fcs · HR-44-V1_cells_found_normalized_Granulocytes.fcs · HR-44-V1_cells_found_normalized_Lymphocytes.fcs · HR-44-V2_cells_found_normalized_Granulocytes.fcs · HR-44-V2_cells_found_normalized_Lymphocytes.fcs · HR-44-V3_1_cells_found_normalized_Granulocytes.fcs · HR-44-V3_1_cells_found_normalized_Lymphocytes.fcs · HR-46-V1_cells_found_normalized_Granulocytes.fcs · HR-46-V1_cells_found_normalized_Lymphocytes.fcs · HR-46-V2_cells_found_normalized_Granulocytes.fcs · HR-46-V2_cells_found_normalized_Lymphocytes.fcs · HR-46-V3_cells_found_normalized_Granulocytes.fcs · HR-46-V3_cells_found_normalized_Lymphocytes.fcs · HR-47-V1_cells_found_normalized_Granulocytes.fcs · HR-47-V1_cells_found_normalized_Lymphocytes.fcs · HR-47-V2_cells_found_normalized_Granulocytes.fcs · HR-47-V2_cells_found_normalized_Lymphocytes.fcs · HR-47-V3_cells_found_normalized_Granulocytes.fcs · HR-47-V3_cells_found_normalized_Lymphocytes.fcs · HR-48-V1_cells_found_normalized_Granulocytes.fcs · HR-48-V1_cells_found_normalized_Lymphocytes.fcs · HR-48-V2_cells_found_normalized_Granulocytes.fcs · HR-48-V2_cells_found_normalized_Lymphocytes.fcs · HR-48-V3_cells_found_normalized_Granulocytes.fcs · HR-48-V3_cells_found_normalized_Lymphocytes.fcs · HR-33-V1_cells_found_normalized_Granulocytes.fcs |
| · Non-responder | HR-21-V1_2_cells_found_normalized_Granulocytes.fcs · HR-21-V1_2_cells_found_normalized_Lymphocytes.fcs · HR-21-V2_cells_found_normalized_Granulocytes.fcs · HR-21-V2_cells_found_normalized_Lymphocytes.fcs · HR-21-V3_cells_found_normalized_Granulocytes.fcs · HR-21-V3_cells_found_normalized_Lymphocytes.fcs · HR-23-V1_cells_found_normalized_Granulocytes.fcs · HR-23-V1_cells_found_normalized_Lymphocytes.fcs · HR-23-V2_cells_found_normalized_Granulocytes.fcs · HR-23-V2_cells_found_normalized_Lymphocytes.fcs · HR-23-V3_cells_found_normalized_Granulocytes.fcs · HR-23-V3_cells_found_normalized_Lymphocytes.fcs · HR-26-V1_cells_found_normalized_Granulocytes.fcs · HR-26-V1_cells_found_normalized_Lymphocytes.fcs · HR-26-V2_cells_found_normalized_Granulocytes.fcs · HR-26-V2_cells_found_normalized_Lymphocytes.fcs · HR-26-V3_cells_found_normalized_Granulocytes.fcs · HR-26-V3_cells_found_normalized_Lymphocytes.fcs · HR-27-V1_cells_found_normalized_Granulocytes.fcs · HR-27-V1_cells_found_normalized_Lymphocytes.fcs · HR-27-V2_cells_found_normalized_Granulocytes.fcs · HR-27-V2_cells_found_normalized_Lymphocytes.fcs · HR-27-V3_cells_found_normalized_Granulocytes.fcs · HR-27-V3_cells_found_normalized_Lymphocytes.fcs · HR-30-V1_cells_found_normalized_Lymphocytes.fcs · HR-30-V2_cells_found_normalized_Granulocytes.fcs · HR-30-V2_cells_found_normalized_Lymphocytes.fcs · HR-30-V3_cells_found_normalized_Granulocytes.fcs · HR-30-V3_cells_found_normalized_Lymphocytes.fcs · HR-32-V1_cells_found_normalized_Granulocytes.fcs · HR-32-V1_cells_found_normalized_Lymphocytes.fcs · HR-32-V2_cells_found_normalized_Granulocytes.fcs · HR-32-V2_cells_found_normalized_Lymphocytes.fcs · HR-32-V3_cells_found_normalized_Lymphocytes.fcs · HR-36-V1_cells_found_normalized_Granulocytes.fcs · HR-36-V1_cells_found_normalized_Lymphocytes.fcs · HR-36-V2_cells_found_normalized_Granulocytes.fcs · HR-36-V2_cells_found_normalized_Lymphocytes.fcs · HR-36-V3_cells_found_normalized_Granulocytes.fcs · HR-36-V3_cells_found_normalized_Lymphocytes.fcs · HR-37-V1_cells_found_normalized_Granulocytes.fcs · HR-37-V1_cells_found_normalized_Lymphocytes.fcs · HR-37-V2_cells_found_normalized_Granulocytes.fcs · HR-37-V2_cells_found_normalized_Lymphocytes.fcs · HR-37-V3_cells_found_normalized_Granulocytes.fcs · HR-37-V3_cells_found_normalized_Lymphocytes.fcs · HR-38-V1_cells_found_normalized_Granulocytes.fcs · HR-38-V1_cells_found_normalized_Lymphocytes.fcs · HR-38-V2_cells_found_normalized_Granulocytes.fcs · HR-38-V2_cells_found_normalized_Lymphocytes.fcs · HR-38-V3_cells_found_normalized_Granulocytes.fcs · HR-38-V3_cells_found_normalized_Lymphocytes.fcs · HR-32-V3_cells_found_normalized_Granulocytes.fcs |
| Timepoints | |
|---|---|
| · Baseline | HR-20-V1_cells_found_normalized_Granulocytes.fcs · HR-20-V1_cells_found_normalized_Lymphocytes.fcs · HR-21-V1_2_cells_found_normalized_Granulocytes.fcs · HR-21-V1_2_cells_found_normalized_Lymphocytes.fcs · HR-22-V1_cells_found_normalized_Granulocytes.fcs · HR-22-V1_cells_found_normalized_Lymphocytes.fcs · HR-23-V1_cells_found_normalized_Granulocytes.fcs · HR-23-V1_cells_found_normalized_Lymphocytes.fcs · HR-24-V1_cells_found_normalized_Granulocytes.fcs · HR-24-V1_cells_found_normalized_Lymphocytes.fcs · HR-26-V1_cells_found_normalized_Granulocytes.fcs · HR-26-V1_cells_found_normalized_Lymphocytes.fcs · HR-27-V1_cells_found_normalized_Granulocytes.fcs · HR-27-V1_cells_found_normalized_Lymphocytes.fcs · HR-28-V1_cells_found_normalized_Granulocytes.fcs · HR-28-V1_cells_found_normalized_Lymphocytes.fcs · HR-29-V1_cells_found_normalized_Granulocytes.fcs · HR-29-V1_cells_found_normalized_Lymphocytes.fcs · HR-30-V1_cells_found_normalized_Granulocytes.fcs · HR-30-V1_cells_found_normalized_Lymphocytes.fcs · HR-31-V1_1_cells_found_normalized_Granulocytes.fcs · HR-31-V1_1_cells_found_normalized_Lymphocytes.fcs · HR-32-V1_cells_found_normalized_Granulocytes.fcs · HR-32-V1_cells_found_normalized_Lymphocytes.fcs · HR-33-V1_cells_found_normalized_Lymphocytes.fcs · HR-35-V1_cells_found_normalized_Granulocytes.fcs · HR-35-V1_cells_found_normalized_Lymphocytes.fcs · HR-36-V1_cells_found_normalized_Granulocytes.fcs · HR-36-V1_cells_found_normalized_Lymphocytes.fcs · HR-37-V1_cells_found_normalized_Granulocytes.fcs · HR-37-V1_cells_found_normalized_Lymphocytes.fcs · HR-38-V1_cells_found_normalized_Granulocytes.fcs · HR-38-V1_cells_found_normalized_Lymphocytes.fcs · HR-39-V1_cells_found_normalized_Granulocytes.fcs · HR-39-V1_cells_found_normalized_Lymphocytes.fcs · HR-40-V1_cells_found_normalized_Granulocytes.fcs · HR-40-V1_cells_found_normalized_Lymphocytes.fcs · HR-42-V1_cells_found_normalized_Granulocytes.fcs · HR-42-V1_cells_found_normalized_Lymphocytes.fcs · HR-44-V1_cells_found_normalized_Granulocytes.fcs · HR-44-V1_cells_found_normalized_Lymphocytes.fcs · HR-46-V1_cells_found_normalized_Granulocytes.fcs · HR-46-V1_cells_found_normalized_Lymphocytes.fcs · HR-47-V1_cells_found_normalized_Granulocytes.fcs · HR-47-V1_cells_found_normalized_Lymphocytes.fcs · HR-48-V1_cells_found_normalized_Granulocytes.fcs · HR-48-V1_cells_found_normalized_Lymphocytes.fcs · HR-33-V1_cells_found_normalized_Granulocytes.fcs |
| · W2 | HR-20-V2_cells_found_normalized_Granulocytes.fcs · HR-20-V2_cells_found_normalized_Lymphocytes.fcs · HR-21-V2_cells_found_normalized_Granulocytes.fcs · HR-21-V2_cells_found_normalized_Lymphocytes.fcs · HR-22-V2_cells_found_normalized_Granulocytes.fcs · HR-22-V2_cells_found_normalized_Lymphocytes.fcs · HR-23-V2_cells_found_normalized_Granulocytes.fcs · HR-23-V2_cells_found_normalized_Lymphocytes.fcs · HR-24-V2_cells_found_normalized_Granulocytes.fcs · HR-24-V2_cells_found_normalized_Lymphocytes.fcs · HR-26-V2_cells_found_normalized_Granulocytes.fcs · HR-26-V2_cells_found_normalized_Lymphocytes.fcs · HR-27-V2_cells_found_normalized_Granulocytes.fcs · HR-27-V2_cells_found_normalized_Lymphocytes.fcs · HR-28-V2_cells_found_normalized_Granulocytes.fcs · HR-28-V2_cells_found_normalized_Lymphocytes.fcs · HR-29-V2_cells_found_normalized_Granulocytes.fcs · HR-29-V2_cells_found_normalized_Lymphocytes.fcs · HR-30-V2_cells_found_normalized_Granulocytes.fcs · HR-30-V2_cells_found_normalized_Lymphocytes.fcs · HR-31-V2_1_cells_found_normalized_Granulocytes.fcs · HR-31-V2_1_cells_found_normalized_Lymphocytes.fcs · HR-32-V2_cells_found_normalized_Granulocytes.fcs · HR-32-V2_cells_found_normalized_Lymphocytes.fcs · HR-33-V2_cells_found_normalized_Granulocytes.fcs · HR-33-V2_cells_found_normalized_Lymphocytes.fcs · HR-35-V2_cells_found_normalized_Granulocytes.fcs · HR-35-V2_cells_found_normalized_Lymphocytes.fcs · HR-36-V2_cells_found_normalized_Granulocytes.fcs · HR-36-V2_cells_found_normalized_Lymphocytes.fcs · HR-37-V2_cells_found_normalized_Granulocytes.fcs · HR-37-V2_cells_found_normalized_Lymphocytes.fcs · HR-38-V2_cells_found_normalized_Granulocytes.fcs · HR-38-V2_cells_found_normalized_Lymphocytes.fcs · HR-39-V2_cells_found_normalized_Granulocytes.fcs · HR-39-V2_cells_found_normalized_Lymphocytes.fcs · HR-40-V2_cells_found_normalized_Granulocytes.fcs · HR-40-V2_cells_found_normalized_Lymphocytes.fcs · HR-42-V2_cells_found_normalized_Granulocytes.fcs · HR-42-V2_cells_found_normalized_Lymphocytes.fcs · HR-44-V2_cells_found_normalized_Granulocytes.fcs · HR-44-V2_cells_found_normalized_Lymphocytes.fcs · HR-46-V2_cells_found_normalized_Granulocytes.fcs · HR-46-V2_cells_found_normalized_Lymphocytes.fcs · HR-47-V2_cells_found_normalized_Granulocytes.fcs · HR-47-V2_cells_found_normalized_Lymphocytes.fcs · HR-48-V2_cells_found_normalized_Granulocytes.fcs · HR-48-V2_cells_found_normalized_Lymphocytes.fcs |
| · W14 | HR-20-V3_cells_found_normalized_Granulocytes.fcs · HR-20-V3_cells_found_normalized_Lymphocytes.fcs · HR-21-V3_cells_found_normalized_Granulocytes.fcs · HR-21-V3_cells_found_normalized_Lymphocytes.fcs · HR-22-V3_cells_found_normalized_Granulocytes.fcs · HR-22-V3_cells_found_normalized_Lymphocytes.fcs · HR-23-V3_cells_found_normalized_Granulocytes.fcs · HR-23-V3_cells_found_normalized_Lymphocytes.fcs · HR-24-V3_cells_found_normalized_Granulocytes.fcs · HR-24-V3_cells_found_normalized_Lymphocytes.fcs · HR-26-V3_cells_found_normalized_Granulocytes.fcs · HR-26-V3_cells_found_normalized_Lymphocytes.fcs · HR-27-V3_cells_found_normalized_Granulocytes.fcs · HR-27-V3_cells_found_normalized_Lymphocytes.fcs · HR-28-V3_cells_found_normalized_Granulocytes.fcs · HR-28-V3_cells_found_normalized_Lymphocytes.fcs · HR-29-V3_cells_found_normalized_Granulocytes.fcs · HR-29-V3_cells_found_normalized_Lymphocytes.fcs · HR-30-V3_cells_found_normalized_Granulocytes.fcs · HR-30-V3_cells_found_normalized_Lymphocytes.fcs · HR-31-V3_cells_found_normalized_Granulocytes.fcs · HR-31-V3_cells_found_normalized_Lymphocytes.fcs · HR-32-V3_cells_found_normalized_Lymphocytes.fcs · HR-33-V3_cells_found_normalized_Granulocytes.fcs · HR-33-V3_cells_found_normalized_Lymphocytes.fcs · HR-35-V3_cells_found_normalized_Granulocytes.fcs · HR-35-V3_cells_found_normalized_Lymphocytes.fcs · HR-36-V3_cells_found_normalized_Granulocytes.fcs · HR-36-V3_cells_found_normalized_Lymphocytes.fcs · HR-37-V3_cells_found_normalized_Granulocytes.fcs · HR-37-V3_cells_found_normalized_Lymphocytes.fcs · HR-38-V3_cells_found_normalized_Granulocytes.fcs · HR-38-V3_cells_found_normalized_Lymphocytes.fcs · HR-39-V3_cells_found_normalized_Granulocytes.fcs · HR-39-V3_cells_found_normalized_Lymphocytes.fcs · HR-40-V3_cells_found_normalized_Granulocytes.fcs · HR-40-V3_cells_found_normalized_Lymphocytes.fcs · HR-42-V3_cells_found_normalized_Granulocytes.fcs · HR-42-V3_cells_found_normalized_Lymphocytes.fcs · HR-44-V3_1_cells_found_normalized_Granulocytes.fcs · HR-44-V3_1_cells_found_normalized_Lymphocytes.fcs · HR-46-V3_cells_found_normalized_Granulocytes.fcs · HR-46-V3_cells_found_normalized_Lymphocytes.fcs · HR-47-V3_cells_found_normalized_Granulocytes.fcs · HR-47-V3_cells_found_normalized_Lymphocytes.fcs · HR-48-V3_cells_found_normalized_Granulocytes.fcs · HR-48-V3_cells_found_normalized_Lymphocytes.fcs · HR-32-V3_cells_found_normalized_Granulocytes.fcs |
| Sample Type | |
|---|---|
| · Whole blood granulocytes | HR-20-V1_cells_found_normalized_Granulocytes.fcs · HR-20-V2_cells_found_normalized_Granulocytes.fcs · HR-20-V3_cells_found_normalized_Granulocytes.fcs · HR-21-V1_2_cells_found_normalized_Granulocytes.fcs · HR-21-V2_cells_found_normalized_Granulocytes.fcs · HR-21-V3_cells_found_normalized_Granulocytes.fcs · HR-22-V1_cells_found_normalized_Granulocytes.fcs · HR-22-V2_cells_found_normalized_Granulocytes.fcs · HR-22-V3_cells_found_normalized_Granulocytes.fcs · HR-23-V1_cells_found_normalized_Granulocytes.fcs · HR-23-V2_cells_found_normalized_Granulocytes.fcs · HR-23-V3_cells_found_normalized_Granulocytes.fcs · HR-24-V1_cells_found_normalized_Granulocytes.fcs · HR-24-V2_cells_found_normalized_Granulocytes.fcs · HR-24-V3_cells_found_normalized_Granulocytes.fcs · HR-26-V1_cells_found_normalized_Granulocytes.fcs · HR-26-V2_cells_found_normalized_Granulocytes.fcs · HR-26-V3_cells_found_normalized_Granulocytes.fcs · HR-27-V1_cells_found_normalized_Granulocytes.fcs · HR-27-V2_cells_found_normalized_Granulocytes.fcs · HR-27-V3_cells_found_normalized_Granulocytes.fcs · HR-28-V1_cells_found_normalized_Granulocytes.fcs · HR-28-V2_cells_found_normalized_Granulocytes.fcs · HR-28-V3_cells_found_normalized_Granulocytes.fcs · HR-29-V1_cells_found_normalized_Granulocytes.fcs · HR-29-V2_cells_found_normalized_Granulocytes.fcs · HR-29-V3_cells_found_normalized_Granulocytes.fcs · HR-30-V1_cells_found_normalized_Granulocytes.fcs · HR-30-V2_cells_found_normalized_Granulocytes.fcs · HR-30-V3_cells_found_normalized_Granulocytes.fcs · HR-31-V1_1_cells_found_normalized_Granulocytes.fcs · HR-31-V2_1_cells_found_normalized_Granulocytes.fcs · HR-31-V3_cells_found_normalized_Granulocytes.fcs · HR-32-V1_cells_found_normalized_Granulocytes.fcs · HR-32-V2_cells_found_normalized_Granulocytes.fcs · HR-33-V2_cells_found_normalized_Granulocytes.fcs · HR-33-V3_cells_found_normalized_Granulocytes.fcs · HR-35-V1_cells_found_normalized_Granulocytes.fcs · HR-35-V2_cells_found_normalized_Granulocytes.fcs · HR-35-V3_cells_found_normalized_Granulocytes.fcs · HR-36-V1_cells_found_normalized_Granulocytes.fcs · HR-36-V2_cells_found_normalized_Granulocytes.fcs · HR-36-V3_cells_found_normalized_Granulocytes.fcs · HR-37-V1_cells_found_normalized_Granulocytes.fcs · HR-37-V2_cells_found_normalized_Granulocytes.fcs · HR-37-V3_cells_found_normalized_Granulocytes.fcs · HR-38-V1_cells_found_normalized_Granulocytes.fcs · HR-38-V2_cells_found_normalized_Granulocytes.fcs · HR-38-V3_cells_found_normalized_Granulocytes.fcs · HR-39-V1_cells_found_normalized_Granulocytes.fcs · HR-39-V2_cells_found_normalized_Granulocytes.fcs · HR-39-V3_cells_found_normalized_Granulocytes.fcs · HR-40-V1_cells_found_normalized_Granulocytes.fcs · HR-40-V2_cells_found_normalized_Granulocytes.fcs · HR-40-V3_cells_found_normalized_Granulocytes.fcs · HR-42-V1_cells_found_normalized_Granulocytes.fcs · HR-42-V2_cells_found_normalized_Granulocytes.fcs · HR-42-V3_cells_found_normalized_Granulocytes.fcs · HR-44-V1_cells_found_normalized_Granulocytes.fcs · HR-44-V2_cells_found_normalized_Granulocytes.fcs · HR-44-V3_1_cells_found_normalized_Granulocytes.fcs · HR-46-V1_cells_found_normalized_Granulocytes.fcs · HR-46-V2_cells_found_normalized_Granulocytes.fcs · HR-46-V3_cells_found_normalized_Granulocytes.fcs · HR-47-V1_cells_found_normalized_Granulocytes.fcs · HR-47-V2_cells_found_normalized_Granulocytes.fcs · HR-47-V3_cells_found_normalized_Granulocytes.fcs · HR-48-V1_cells_found_normalized_Granulocytes.fcs · HR-48-V2_cells_found_normalized_Granulocytes.fcs · HR-48-V3_cells_found_normalized_Granulocytes.fcs · HR-32-V3_cells_found_normalized_Granulocytes.fcs · HR-33-V1_cells_found_normalized_Granulocytes.fcs |
| · Whole blood lymphocytes | HR-20-V1_cells_found_normalized_Lymphocytes.fcs · HR-20-V2_cells_found_normalized_Lymphocytes.fcs · HR-20-V3_cells_found_normalized_Lymphocytes.fcs · HR-21-V1_2_cells_found_normalized_Lymphocytes.fcs · HR-21-V2_cells_found_normalized_Lymphocytes.fcs · HR-21-V3_cells_found_normalized_Lymphocytes.fcs · HR-22-V1_cells_found_normalized_Lymphocytes.fcs · HR-22-V2_cells_found_normalized_Lymphocytes.fcs · HR-22-V3_cells_found_normalized_Lymphocytes.fcs · HR-23-V1_cells_found_normalized_Lymphocytes.fcs · HR-23-V2_cells_found_normalized_Lymphocytes.fcs · HR-23-V3_cells_found_normalized_Lymphocytes.fcs · HR-24-V1_cells_found_normalized_Lymphocytes.fcs · HR-24-V2_cells_found_normalized_Lymphocytes.fcs · HR-24-V3_cells_found_normalized_Lymphocytes.fcs · HR-26-V1_cells_found_normalized_Lymphocytes.fcs · HR-26-V2_cells_found_normalized_Lymphocytes.fcs · HR-26-V3_cells_found_normalized_Lymphocytes.fcs · HR-27-V1_cells_found_normalized_Lymphocytes.fcs · HR-27-V2_cells_found_normalized_Lymphocytes.fcs · HR-27-V3_cells_found_normalized_Lymphocytes.fcs · HR-28-V1_cells_found_normalized_Lymphocytes.fcs · HR-28-V2_cells_found_normalized_Lymphocytes.fcs · HR-28-V3_cells_found_normalized_Lymphocytes.fcs · HR-29-V1_cells_found_normalized_Lymphocytes.fcs · HR-29-V2_cells_found_normalized_Lymphocytes.fcs · HR-29-V3_cells_found_normalized_Lymphocytes.fcs · HR-30-V1_cells_found_normalized_Lymphocytes.fcs · HR-30-V2_cells_found_normalized_Lymphocytes.fcs · HR-30-V3_cells_found_normalized_Lymphocytes.fcs · HR-31-V1_1_cells_found_normalized_Lymphocytes.fcs · HR-31-V2_1_cells_found_normalized_Lymphocytes.fcs · HR-31-V3_cells_found_normalized_Lymphocytes.fcs · HR-32-V1_cells_found_normalized_Lymphocytes.fcs · HR-32-V2_cells_found_normalized_Lymphocytes.fcs · HR-32-V3_cells_found_normalized_Lymphocytes.fcs · HR-33-V1_cells_found_normalized_Lymphocytes.fcs · HR-33-V2_cells_found_normalized_Lymphocytes.fcs · HR-33-V3_cells_found_normalized_Lymphocytes.fcs · HR-35-V1_cells_found_normalized_Lymphocytes.fcs · HR-35-V2_cells_found_normalized_Lymphocytes.fcs · HR-35-V3_cells_found_normalized_Lymphocytes.fcs · HR-36-V1_cells_found_normalized_Lymphocytes.fcs · HR-36-V2_cells_found_normalized_Lymphocytes.fcs · HR-36-V3_cells_found_normalized_Lymphocytes.fcs · HR-37-V1_cells_found_normalized_Lymphocytes.fcs · HR-37-V2_cells_found_normalized_Lymphocytes.fcs · HR-37-V3_cells_found_normalized_Lymphocytes.fcs · HR-38-V1_cells_found_normalized_Lymphocytes.fcs · HR-38-V2_cells_found_normalized_Lymphocytes.fcs · HR-38-V3_cells_found_normalized_Lymphocytes.fcs · HR-39-V1_cells_found_normalized_Lymphocytes.fcs · HR-39-V2_cells_found_normalized_Lymphocytes.fcs · HR-39-V3_cells_found_normalized_Lymphocytes.fcs · HR-40-V1_cells_found_normalized_Lymphocytes.fcs · HR-40-V2_cells_found_normalized_Lymphocytes.fcs · HR-40-V3_cells_found_normalized_Lymphocytes.fcs · HR-42-V1_cells_found_normalized_Lymphocytes.fcs · HR-42-V2_cells_found_normalized_Lymphocytes.fcs · HR-42-V3_cells_found_normalized_Lymphocytes.fcs · HR-44-V1_cells_found_normalized_Lymphocytes.fcs · HR-44-V2_cells_found_normalized_Lymphocytes.fcs · HR-44-V3_1_cells_found_normalized_Lymphocytes.fcs · HR-46-V1_cells_found_normalized_Lymphocytes.fcs · HR-46-V2_cells_found_normalized_Lymphocytes.fcs · HR-46-V3_cells_found_normalized_Lymphocytes.fcs · HR-47-V1_cells_found_normalized_Lymphocytes.fcs · HR-47-V2_cells_found_normalized_Lymphocytes.fcs · HR-47-V3_cells_found_normalized_Lymphocytes.fcs · HR-48-V1_cells_found_normalized_Lymphocytes.fcs · HR-48-V2_cells_found_normalized_Lymphocytes.fcs · HR-48-V3_cells_found_normalized_Lymphocytes.fcs |
